Borrelia burgdorferi, the causative agent of Lyme disease, forms drug-tolerant persister cells.Borrelia burgdorferi Persistence: Consensus and Controversy – where do we go from here? This was presented in CDC Webinar on persistence see link above.
Researchers’ discovery may explain difficulty in treating Lyme disease -
This is the first time, we think, that pulse-dosing has been published as a method for eradicating the population of a pathogen with antibiotics that don’t kill dormant cells,” Lewis said. “The trick to doing this is to allow the dormant cells to wake up.”
Other videos of Prof Lewis Principles of Antibiotic Discovery - Kim Lewis
What lights my fire https://www.youtube.com/watch?v=GBZ9hyrMsoM
Prof Lewis featured in a recent BBC documentary on Panorama on his research into finding new antibiotics
and earlier http://www.bbc.co.uk/news/health-30657486